SCHEMBL3274334

SCHEMBL3274334

O=C(O)c1cc2c(cc1C(=O)O)C(c1ccccc1)(c1ccccc1)c1cc(C(=O)O)c(C(=O)O)cc1O2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
CYP2C9 P11712 1/20 0.40
ALDH1A1 P00352 4/20 0.39
ALOX15 P16050 1/20 0.39
POLB P06746 3/20 0.36
HSD17B10 Q99714 2/20 0.36
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34
KDM4E B2RXH2 2/20 0.34
HPGD P15428 2/20 0.34
CA2 P00918 1/20 0.34
HMGB1 P09429 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21436917 0.84 ALOX5 (0.36) ALOX5CYP2C9ALDH1A1ALOX15HSD17B10
SCHEMBL8984589 0.83 TDP1 (0.41) ALOX5CYP2C9ALDH1A1ALOX15POLB
SCHEMBL3271333 0.83 ALOX5 (0.39) ALOX5CYP2C9ALDH1A1ALOX15POLB
SCHEMBL3775432 0.83 CNR1 (0.34) ALOX5CYP2C9ALDH1A1POLBHSD17B10
SCHEMBL3277451 0.82 RAB9A (0.45) ALDH1A1POLBHSD17B10HPGDSMN1; SMN2
SCHEMBL3277040 0.81 TSHR (0.50) CYP2C9ALDH1A1ALOX15CA12CA1
SCHEMBL1099586 0.80 PDK2 (0.38) ALOX5CYP2C9ALDH1A1ALOX15HSD17B10
SCHEMBL9221863 0.79 PDK2 (0.37) ALOX5CYP2C9ALDH1A1ALOX15HSD17B10
SCHEMBL17238258 0.78 ALOX5 (0.54) ALOX5CYP2C9ALDH1A1HSD17B10KDM4E
SCHEMBL9220858 0.77 PDK2 (0.36) ALOX5CYP2C9ALDH1A1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12091507-B2 Polymers for use in electronic devices DUPONT ELECTRONICS, INC. (US) 2024-09-17 US disclosed
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor United States of America as represented by the Adminstrator of NASA (US) 2023-09-19 US disclosed
US-11725079-B2 Polyimide compositions and articles incorporating the same THE BOEING COMPANY (US) 2023-08-15 US disclosed
US-20220017697-A1 POLYIMIDE COMPOSITIONS AND ARTICLES INCORPORATING THE SAME UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2022-01-20 US disclosed
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2022-01-20 US disclosed
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2021-09-28 US disclosed
CN-112424261-A Polymers for use in electronic devices 杜邦电子公司 2021-02-26 CN disclosed
US-20210017335-A1 Polymers For Use In Electronic Devices U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-01-21 US disclosed
US-20210017335-A1 Polymers For Use In Electronic Devices U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-01-21 US disclosed
US-10808079-B2 Synthesis of copolyimides containing fluorine and silicon surface modifying agents UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-10-20 US disclosed
US-20090226642-A1 LOW COLOR POLYIMIDE COMPOSITIONS USEFUL IN OPTICAL TYPE APPLICATIONS AND METHODS AND COMPOSITIONS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-10 US disclosed
US-7572878-B2 Showing improved thermal stability properties in conjunction with improved optical transparency making these polyimides useful in electronic device applications; replacement for quartz or glass in optical display devices or the like E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-11 US disclosed
US-7550194-B2 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-23 US disclosed
EP-1764381-B1 Polycyclic polyimides and compositions and their corresponding polyamic acids DU PONT (US) 2008-06-18 EP disclosed
US-20080138537-A1 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-06-12 US disclosed
US-20070066734-A1 Polycyclic polyimides and compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2007-03-22 US disclosed
EP-1764381-A1 Polycyclic polyimides and compositions and their corresponding polyamic acids E.I.Du pont de nemours and company (US) 2007-03-21 EP disclosed
EP-1749850-A1 Low color polyimide compositions useful in optical type applications and methods and compositions related thereto E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-02-07 EP disclosed
EP-0646406-B1 Polyimide gas separation membranes AIR LIQUIDE (FR) 1998-08-26 EP disclosed
US-5334697-A Contains repeating units derived from 9,9-disubstituted xanthene dianhydride L'AIR LIQUIDE, S.A. (FR) 1994-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS ALOX5 2145/4885CYP2C9 2003/4885ALDH1A1 3335/4885
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS ALOX5 2145/4885CYP2C9 2003/4885ALDH1A1 3335/4885
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS ALOX5 2145/4885CYP2C9 2003/4885ALDH1A1 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.