Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 11/20 | 0.49 |
| ▸ | HTR1A | P08908 | 10/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21216375 | 0.80 | HRH3 (0.51) | DRD2HTR1ADRD1 | |
| SCHEMBL30238474 | 0.80 | HRH3 (0.51) | DRD2HTR1ADRD1 | |
| SCHEMBL3957205 | 0.77 | ADRA1D (0.62) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL16269635 | 0.76 | S1PR5 (0.47) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL1135880 | 0.76 | BCL2L1 (0.42) | DRD2DRD1 | |
| SCHEMBL20292711 | 0.76 | CARM1 (0.46) | — | |
| Bromide SCHEMBL6521671 | 0.76 | ADRA1D (0.61) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL8493216 | 0.74 | SIGMAR1 (0.50) | — | |
| SCHEMBL22129231 | 0.72 | DRD2 (0.49) | DRD2HTR1ADRD1 | |
| SCHEMBL22424511 | 0.72 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135084-A2 | Tetrahydroisoquinolincarbamic-acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1985-03-27 | — | — | EP | disclosed |