SCHEMBL22129231

SCHEMBL22129231

C=CCN1CCc2c(O)cccc21

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 14/20 0.49
HTR1A P08908 13/20 0.49
DRD1 P21728 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15787244 0.91 DRD2 (0.47) DRD2HTR1ADRD1
SCHEMBL2271564 0.78 HRH3 (0.41) DRD2HTR1ADRD1
Bromide SCHEMBL6844504 0.77 HRH3 (0.40) DRD2HTR1ADRD1
SCHEMBL8493200 0.77 MEN1 (0.42) DRD2HTR1ADRD1
SCHEMBL8497315 0.74 ALDH1A1 (0.40) DRD2HTR1ADRD1
SCHEMBL11345303 0.74 HTR6 (0.52)
SCHEMBL11063088 0.74 HTR1A (0.40) DRD2HTR1A
SCHEMBL8496611 0.73 DRD2 (0.40) DRD2HTR1ADRD1
SCHEMBL19949789 0.73 ADRA1D (0.42) HTR1A
SCHEMBL4632488 0.73 ALDH1A1 (0.63) HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020124688-A1 FULL-SPECTRUM HIGH-BRIGHTNESS AND HIGH-STABILITY FLUORESCENT DYES, AND SYNTHESIS AND APPLICATION THEREOF 中国科学院大连化学物理研究所 2020-06-25 WO claimed
WO-2020124688-A1 FULL-SPECTRUM HIGH-BRIGHTNESS AND HIGH-STABILITY FLUORESCENT DYES, AND SYNTHESIS AND APPLICATION THEREOF 中国科学院大连化学物理研究所 2020-06-25 WO disclosed