Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977245 | 0.87 | ALDH1A1 (0.53) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL6241091 | 0.82 | LMNA (0.63) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL7158963 | 0.81 | KDM4E (0.49) | LMNAALDH1A1KDM4EHPGDHSD17B10 | |
| Fluoride SCHEMBL5144825 | 0.80 | LMNA (0.61) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10857506 | 0.80 | HPGD (0.44) | LMNAALDH1A1POLBKDM4EHPGD | |
| SCHEMBL11000199 | 0.80 | ALDH1A1 (0.43) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL5144832 | 0.79 | LMNA (0.60) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL27788932 | 0.78 | DPP4 (0.41) | LMNAALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL16469277 | 0.78 | KMT2A (0.50) | LMNAALDH1A1TSHRMAPTTHRB | |
| SCHEMBL25069783 | 0.78 | POLB (0.50) | LMNAALDH1A1TSHRMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160578-A1 | 1,8-Naphthyridine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0132845-A2 | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1985-02-13 | — | — | EP | disclosed |