Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654948 | 0.82 | ADRB2 (0.46) | ALDH1A1TSHRHPGDMAPTTHRB | |
| SCHEMBL10996251 | 0.80 | LMNA (0.48) | ALDH1A1TSHRHPGDMAPTTHRB | |
| SCHEMBL11283380 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDMAPTTHRB | |
| SCHEMBL10929161 | 0.72 | ADRB2 (0.45) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL7158963 | 0.72 | KDM4E (0.49) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL10548813 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRHPGDMAPTTHRB | |
| SCHEMBL9837371 | 0.70 | LMNA (0.60) | ALDH1A1TSHRHPGDLMNACYP2C9 | |
| SCHEMBL11047766 | 0.69 | LMNA (0.50) | ALDH1A1TSHRHPGDMAPTTHRB | |
| SCHEMBL11200215 | 0.69 | KMT2A (0.48) | ALDH1A1TSHRHPGDMAPTTHRB | |
| SCHEMBL3977245 | 0.69 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132845-A2 | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1985-02-13 | — | — | EP | disclosed |