Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000171 | 0.79 | AHR (0.43) | RGS4AHRLMNAKDM4EALDH1A1 | |
| SCHEMBL3213620 | 0.78 | GSK3A (0.50) | RGS4KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL6809868 | 0.76 | RGS4 (0.48) | RGS4LMNAALDH1A1MAPTGAA | |
| SCHEMBL1535501 | 0.75 | RGS4 (0.58) | RGS4LMNAALDH1A1MAPTGAA | |
| SCHEMBL3205446 | 0.74 | HTR2A (0.43) | RGS4L3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL1471569 | 0.71 | RAD51 (0.44) | RGS4AHRLMNAALDH1A1MAPT | |
| SCHEMBL20216186 | 0.69 | ALDH1A1 (0.48) | RGS4L3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL7579280 | 0.68 | MAPT (0.72) | RGS4AHRLMNAALDH1A1MAPT | |
| SCHEMBL15355922 | 0.68 | RGS4 (0.41) | RGS4LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL4774013 | 0.66 | PGR (0.43) | LMNAMAPTNPSR1CACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529736-A | Antidepressant | AMERICAN CYANAMID COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0100426-A1 | 3a-(substituted-phenyl)-hexaloctahydro-4,7-alkanoisoindoles | AMERICAN CYANAMID COMPANY (US) | 1984-02-15 | — | — | EP | disclosed |