Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502995 | 0.92 | TSHR (0.47) | CYP2C9TSHRABCB11TBXA2RADRA1A | |
| SCHEMBL10502872 | 0.91 | KDM4E (0.45) | CYP2C9TSHRABCB11TBXA2RADRA1A | |
| SCHEMBL10785514 | 0.87 | CYP2C9 (0.64) | CYP2C9TSHRABCB11TBXA2RADRA1A | |
| SCHEMBL10503699 | 0.85 | CACNA1F (0.41) | TP53CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10502213 | 0.84 | GAA (0.40) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL11035332 | 0.83 | DHFR (0.44) | CYP2C9TSHRKDM4EMEN1CYP1A2 | |
| SCHEMBL10503261 | 0.82 | CYP2C9 (0.48) | CYP2C9TSHRABCB11TBXA2RADRA1A | |
| SCHEMBL10746130 | 0.81 | ACHE (0.43) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10502291 | 0.81 | TSHR (0.37) | CYP2C9TSHRABCB11TBXA2RADRA1A | |
| SCHEMBL10786737 | 0.81 | ALDH1A1 (0.60) | CYP2C9TSHRABCB11TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133530-A2 | 1,6-Naphthyridinone derivatives, process for their preparation, and medicaments containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1985-02-27 | — | — | EP | disclosed |