Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924898 | 0.87 | L3MBTL1 (0.47) | L3MBTL1MAPTNPSR1MAPK1HTR2A | |
| SCHEMBL5372821 | 0.81 | NR4A1 (0.54) | MAPTTSHR | |
| SCHEMBL24155484 | 0.81 | MAPT (0.50) | L3MBTL1MAPTNPSR1LTA4HKIF11 | |
| SCHEMBL21359797 | 0.80 | MAOB (0.55) | MAPTLTA4HTSHRATMRAB9A | |
| SCHEMBL12868961 | 0.79 | LTA4H (0.49) | L3MBTL1MAPTLTA4HKIF11TTBK1 | |
| SCHEMBL9861579 | 0.78 | PDE2A (0.44) | L3MBTL1MAPTNPSR1KIF11TSHR | |
| SCHEMBL27579381 | 0.78 | LTA4H (0.59) | L3MBTL1MAPTNPSR1LTA4HKIF11 | |
| SCHEMBL9798371 | 0.78 | LTA4H (0.54) | L3MBTL1MAPTNPSR1LTA4HKIF11 | |
| SCHEMBL14020503 | 0.77 | PPARG (0.51) | L3MBTL1MAPTLTA4HKIF11HTR2A | |
| SCHEMBL476378 | 0.77 | ALDH1A1 (0.66) | L3MBTL1MAPTNPSR1LTA4HKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135155-A2 | Barbituric acid derivatives | CIBA-GEIGY AG (CH) | 1985-03-27 | — | — | EP | disclosed |