Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489049 | 0.86 | NPSR1 (0.48) | MAPTL3MBTL1NPSR1ALDH1A1KDM4E | |
| SCHEMBL9541829 | 0.85 | L3MBTL1 (0.50) | MAPTL3MBTL1NPSR1ALDH1A1TSHR | |
| SCHEMBL21701049 | 0.85 | ALDH1A1 (0.49) | MAPTL3MBTL1NPSR1ALDH1A1KDM4E | |
| SCHEMBL9596150 | 0.83 | ALDH1A1 (0.57) | MAPTL3MBTL1ALDH1A1TSHRF10 | |
| SCHEMBL4608873 | 0.82 | MAPT (0.55) | MAPTL3MBTL1NPSR1ALDH1A1KDM4E | |
| SCHEMBL30768365 | 0.81 | TEAD1 (0.47) | MAPTL3MBTL1NPSR1ALDH1A1KDM4E | |
| SCHEMBL24750328 | 0.81 | TEAD1 (0.47) | MAPTL3MBTL1NPSR1ALDH1A1KDM4E | |
| SCHEMBL24156278 | 0.81 | ALDH1A1 (0.44) | MAPTL3MBTL1NPSR1ALDH1A1KIF11 | |
| SCHEMBL27579381 | 0.81 | LTA4H (0.59) | MAPTL3MBTL1NPSR1ALDH1A1LTA4H | |
| SCHEMBL9798371 | 0.81 | LTA4H (0.54) | MAPTL3MBTL1NPSR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | SLC6A11, SCN1A, SCN1B | MAPT 741/4885L3MBTL1 3361/4885NPSR1 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.