Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073772 | 0.81 | HTT (0.58) | HTTALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL29118559 | 0.80 | KMT2A (0.48) | HTTALDH1A1KMT2AMAPTCYP2C19 | |
| SCHEMBL27596019 | 0.80 | MAPT (0.48) | HTTALDH1A1KMT2AMAPTCYP2C19 | |
| SCHEMBL2283147 | 0.80 | MAPT (0.48) | HTTALDH1A1KMT2AMAPTCYP2C19 | |
| SCHEMBL10518614 | 0.79 | MAPT (0.47) | HTTALDH1A1KMT2AMAPTCYP2C19 | |
| SCHEMBL16028069 | 0.79 | MAPT (0.47) | HTTALDH1A1KMT2AMAPTCYP2C19 | |
| SCHEMBL7619909 | 0.78 | SLC6A2 (0.48) | ALDH1A1KMT2AMAPTCYP2C19HIF1A | |
| SCHEMBL29118554 | 0.78 | MAPT (0.46) | HTTALDH1A1KMT2AMAPTCYP2C19 | |
| SCHEMBL27838486 | 0.78 | MAPT (0.46) | KMT2AMAPTCYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL28558462 | 0.76 | CYP2D6 (0.45) | KMT2AMAPTCYP2C19HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0130680-A2 | Cure to elastomers composition | LOCTITE CORPORATION (US) | 1985-01-09 | — | — | EP | disclosed |
| US-4439600-A | Cure to elastomers compositions | LOCTITE CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |