Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629400 | 0.87 | PARP1 (0.54) | MMP13EGFRHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL11005582 | 0.84 | HIF1A (0.47) | ALDH1A1HIF1A | |
| SCHEMBL2142248 | 0.83 | EGFR (0.62) | MMP13EGFRHPGDGLAPRKAA2 | |
| SCHEMBL13210567 | 0.83 | L3MBTL1 (0.76) | MMP13EGFRHPGDGLAPRKAA2 | |
| SCHEMBL12266355 | 0.82 | MMP13 (0.59) | MMP13EGFRHPGDGLAPRKAA2 | |
| SCHEMBL1019074 | 0.82 | L3MBTL1 (0.65) | MMP13EGFRHPGDGLAPRKAA2 | |
| SCHEMBL6434986 | 0.80 | P4HTM (0.62) | L3MBTL1ALDH1A1HIF1ACYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL11633575 | 0.79 | P4HTM (0.61) | L3MBTL1ALDH1A1HIF1ACYP1A2KMT2A | |
| SCHEMBL9967496 | 0.78 | MMP13 (0.55) | MMP13EGFRHPGDGLAPRKAA2 | |
| SCHEMBL3083971 | 0.78 | HTT (0.75) | MMP13HPGDHPGDSHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4109000-A | HYPOTENSIVES | NIPPON SHINYAKU CO., LTD. (JP) | 1978-08-22 | — | — | US | claimed |