Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11006353 | 1.00 | PI4KB (0.53) | PI4KBHCAR1OGFRL1OPRM1OPRD1 | |
| SCHEMBL11116471 | 0.87 | PI4KB (0.43) | PI4KBHCAR1OGFRL1OPRM1OPRD1 | |
| SCHEMBL11007999 | 0.78 | PI4KB (0.60) | PI4KBHCAR1ACSS2KDM4EALDH1A1 | |
| SCHEMBL11008003 | 0.78 | PI4KB (0.60) | PI4KBHCAR1ACSS2KDM4EALDH1A1 | |
| SCHEMBL11015999 | 0.76 | PI4KB (0.69) | PI4KBL3MBTL1TP53RPS6KB1GSK3B | |
| SCHEMBL11016000 | 0.76 | PI4KB (0.69) | PI4KBL3MBTL1TP53RPS6KB1GSK3B | |
| SCHEMBL21311255 | 0.74 | OPRM1 (0.59) | HCAR1OGFRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL2929873 | 0.73 | RPS6KB1 (0.58) | HCAR1OGFRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11557178 | 0.73 | PI4KB (0.51) | PI4KBALDH1A1GFERALK | |
| SCHEMBL11557174 | 0.73 | PI4KB (0.51) | PI4KBALDH1A1GFERALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492708-A | Antiviral benzimidazoles | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | claimed |
| EP-0111993-A2 | Improvements in or relating to benzimidazoles | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | claimed |