Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11006353 | 0.87 | PI4KB (0.53) | PI4KBHCAR1PRKACARPS6KB1GSK3B | |
| SCHEMBL11006351 | 0.87 | PI4KB (0.53) | PI4KBHCAR1PRKACARPS6KB1GSK3B | |
| SCHEMBL11111590 | 0.85 | CNR2 (0.45) | CNR2HCAR1PRKACARPS6KB1GSK3B | |
| SCHEMBL989522 | 0.73 | L3MBTL1 (0.41) | HCAR1RPS6KB1KDM2BHPGDALDH1A1 | |
| SCHEMBL21310911 | 0.73 | ALDH1A1 (0.52) | HCAR1RPS6KB1ALDH1A1ALOX15OPRM1 | |
| SCHEMBL2361982 | 0.72 | TP53 (0.43) | HCAR1PRKACARPS6KB1GSK3BROCK1 | |
| SCHEMBL2360920 | 0.72 | HCAR1 (0.50) | HCAR1PRKACARPS6KB1GSK3BROCK1 | |
| SCHEMBL2362323 | 0.70 | CYP11B2 (0.50) | HCAR1PRKACARPS6KB1GSK3BROCK1 | |
| SCHEMBL2343261 | 0.70 | OPRM1 (0.42) | HCAR1CYP11B1CYP11B2ALDH1A1OPRM1 | |
| SCHEMBL17582784 | 0.70 | RPS6KB1 (0.48) | RPS6KB1LMNAHPGDALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111993-A2 | Improvements in or relating to benzimidazoles | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | claimed |