Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 6/20 | 0.41 |
| ▸ | PREP | P48147 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008482 | 0.91 | NAAA (0.54) | CTSLCTSBCTSKNAAADPP4 | |
| SCHEMBL11007540 | 0.85 | CTSK (0.41) | CTSLCTSBCTSKPREPMAOB | |
| SCHEMBL11007258 | 0.83 | NAAA (0.48) | CTSLCTSBCTSKNAAADPP4 | |
| SCHEMBL11005524 | 0.83 | KMT2A (0.43) | MAOBSMN1; SMN2DPP4FAPDPP8 | |
| SCHEMBL11002451 | 0.83 | KMT2A (0.40) | CTSLCTSBCTSKSMN1; SMN2DPP4 | |
| SCHEMBL11003582 | 0.82 | IDO1 (0.45) | MAOBSMN1; SMN2DPP4FAPDPP8 | |
| SCHEMBL11008420 | 0.81 | NAAA (0.50) | NAAADPP4FAPDPP8DPP9 | |
| SCHEMBL11008481 | 0.80 | DPP4 (0.42) | NAAADPP4FAPDPP8DPP9 | |
| SCHEMBL11004759 | 0.79 | DPP4 (0.41) | DPP4DPP8DPP9 | |
| SCHEMBL11165500 | 0.79 | IDO1 (0.44) | CTSLCTSBCTSKPREPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517183-A | COMBATING DISEASES WITH WEAKNESS OF IMMUNE SYSTEMS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-05-14 | — | — | US | disclosed |
| US-4397848-A | ANTITUMOR ACTIVITY | BOEHRINGER MANNHEIM GMBH (DE) | 1983-08-09 | — | — | US | disclosed |
| EP-0014976-B1 | N-SUBSTITUTED 2-CYANAZIRIDINES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM, CORRESPONDINGLY SUBSTITUTED AZIRIDINE-2-CARBONAMIDES AND THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1982-04-07 | — | — | EP | disclosed |
| EP-0014976-A1 | N-substituted 2-cyanaziridines, methods for their preparation and medicaments containing them, correspondingly substituted aziridine-2-carbonamides and their preparation | Roche Diagnostics GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |