Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | AGXT | P21549 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166191 | 0.86 | IDO1 (0.46) | IDO1AGXTDPP4DPP8DPP9 | |
| SCHEMBL11004925 | 0.82 | IDO1 (0.49) | IDO1DPP4DPP8DPP9DPP7 | |
| SCHEMBL11006655 | 0.82 | CTSL (0.49) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL11010247 | 0.78 | OPRK1 (0.41) | MAOB | |
| SCHEMBL11003313 | 0.75 | IDO1 (0.44) | IDO1DPP4DPP8DPP9DPP7 | |
| SCHEMBL11008077 | 0.74 | CYP4F2 (0.48) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11008482 | 0.74 | NAAA (0.54) | IDO1AGXTDPP4DPP8DPP9 | |
| SCHEMBL11010407 | 0.73 | SIGMAR1 (0.44) | DPP4DPP8ALDH1A1KDM4E | |
| SCHEMBL11007258 | 0.73 | NAAA (0.48) | AGXTDPP4DPP8DPP9DPP7 | |
| SCHEMBL11005524 | 0.73 | KMT2A (0.43) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517183-A | COMBATING DISEASES WITH WEAKNESS OF IMMUNE SYSTEMS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-05-14 | — | — | US | disclosed |
| US-4397848-A | ANTITUMOR ACTIVITY | BOEHRINGER MANNHEIM GMBH (DE) | 1983-08-09 | — | — | US | disclosed |
| EP-0014976-B1 | N-SUBSTITUTED 2-CYANAZIRIDINES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM, CORRESPONDINGLY SUBSTITUTED AZIRIDINE-2-CARBONAMIDES AND THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1982-04-07 | — | — | EP | disclosed |
| EP-0014976-A1 | N-substituted 2-cyanaziridines, methods for their preparation and medicaments containing them, correspondingly substituted aziridine-2-carbonamides and their preparation | Roche Diagnostics GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |