Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.50 |
| ▸ | DPP4 | P27487 | 6/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.44 |
| ▸ | FAP | Q12884 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167676 | 0.93 | AGXT (0.55) | NAAADPP4DPP7FAPDPP8 | |
| SCHEMBL11007258 | 0.84 | NAAA (0.48) | NAAADPP4DPP7FAPDPP8 | |
| SCHEMBL11002451 | 0.81 | KMT2A (0.40) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL11005524 | 0.81 | KMT2A (0.43) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL11010407 | 0.81 | SIGMAR1 (0.44) | NAAADPP4DPP8SIGMAR1 | |
| SCHEMBL11006655 | 0.81 | CTSL (0.49) | NAAADPP4DPP7FAPDPP8 | |
| SCHEMBL11008481 | 0.81 | DPP4 (0.42) | NAAADPP4DPP7FAPDPP8 | |
| SCHEMBL11008482 | 0.79 | NAAA (0.54) | NAAADPP4DPP7FAPDPP8 | |
| SCHEMBL11157958 | 0.78 | AGXT (0.53) | NAAADPP4DPP7FAPDPP8 | |
| SCHEMBL11007278 | 0.77 | PTGS2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517183-A | COMBATING DISEASES WITH WEAKNESS OF IMMUNE SYSTEMS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-05-14 | — | — | US | disclosed |
| EP-0014976-B1 | N-SUBSTITUTED 2-CYANAZIRIDINES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM, CORRESPONDINGLY SUBSTITUTED AZIRIDINE-2-CARBONAMIDES AND THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1982-04-07 | — | — | EP | disclosed |