Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | FABP6 | P51161 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008003 | 0.81 | PI4KB (0.60) | ABL1FABP6SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL11007999 | 0.81 | PI4KB (0.60) | ABL1FABP6SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL11008032 | 0.81 | PI4KB (0.50) | ABL1FABP6SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL11159784 | 0.80 | ABL1 (0.42) | ABL1FABP6SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL18950565 | 0.77 | HSD17B10 (0.70) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11011358 | 0.77 | PDE4A (0.44) | ABL1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL11011359 | 0.77 | PDE4A (0.44) | ABL1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL5809308 | 0.76 | FGFR1 (0.57) | SMN1; SMN2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14247592 | 0.75 | HCAR1 (0.47) | ABL1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL18083357 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2RAB9AMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111993-A2 | Improvements in or relating to benzimidazoles | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | claimed |
| US-4492708-A | Antiviral benzimidazoles | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | disclosed |