SCHEMBL1100877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1100396	0.90	GCGR (0.49)	GCGRGIPRSIRT5TP53MAPT
	SCHEMBL1746924	0.87	KMT2A (0.52)	TP53MAPTALDH1A1L3MBTL1GSTO1
	SCHEMBL1099079	0.85	ATP4A (0.48)	GCGRGIPRATP4AATP4BALDH1A1
	SCHEMBL2647516	0.81	GCGR (0.73)	GCGRGIPR
	SCHEMBL7221406	0.80	MAPT (0.59)	SIRT5TP53MAPTATP4AATP4B
	SCHEMBL1745385	0.79	PPARD (0.55)	GCGRGIPRATP4AATP4B
	SCHEMBL1744789	0.79	KMT2A (0.54)	TP53MAPTALDH1A1L3MBTL1GSTO1
	SCHEMBL3451487	0.79	KMT2A (0.54)	TP53MAPTALDH1A1L3MBTL1GSTO1
	SCHEMBL1198879	0.78	ALDH1A1 (0.56)	GCGRGIPRSIRT5TP53MAPT
	SCHEMBL28715169	0.78	ALDH1A1 (0.56)	GCGRGIPRSIRT5TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.