Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP5 | P51878 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909548 | 0.94 | CTSB (0.53) | RENCTSBCTSK | |
| SCHEMBL11006634 | 0.85 | REN (0.49) | RENCTSBCTSKMMEECE1 | |
| SCHEMBL11013588 | 0.83 | TACR1 (0.61) | CTSBCTSKTACR1CTSLCTSS | |
| SCHEMBL10431182 | 0.83 | CTSL (0.59) | CTSBCTSKTACR1MMEECE1 | |
| SCHEMBL10907851 | 0.81 | CTSK (0.57) | RENCTSBCTSK | |
| SCHEMBL10909792 | 0.80 | CTSB (0.55) | RENCTSBCTSKCASP3CASP7 | |
| SCHEMBL10905628 | 0.80 | CTSK (0.47) | RENCTSBCTSKCTSLCTSS | |
| SCHEMBL11014917 | 0.79 | CTSL (0.46) | CTSBCTSKTACR1CTSLCTSS | |
| SCHEMBL11010919 | 0.79 | CTSB (0.44) | RENCTSBCTSKMMEECE1 | |
| SCHEMBL11011996 | 0.78 | REN (0.57) | RENCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |