Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11012052 | 0.85 | SRD5A1 (0.36) | MEN1KMT2A | |
| SCHEMBL7320987 | 0.73 | MEN1 (0.38) | MMP2ADCY2MEN1HTTKMT2A | |
| SCHEMBL11013024 | 0.72 | ADORA3 (0.36) | RIPK1MEN1HTTKMT2A | |
| SCHEMBL11012610 | 0.69 | SMN1; SMN2 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL23959122 | 0.64 | OPRK1 (0.43) | OPRK1PDE4DLMNAPDE3AMDM2 | |
| SCHEMBL28226709 | 0.64 | CHEK1 (0.53) | OPRK1PDE4DLMNAPDE3ACHRM2 | |
| SCHEMBL11419302 | 0.64 | OPRK1 (0.54) | OPRK1PDE4DLMNAPDE3ACHRM2 | |
| SCHEMBL11097045 | 0.64 | LMNA (0.36) | LMNAMEN1HTTKMT2A | |
| SCHEMBL12429324 | 0.62 | OPRK1 (0.59) | OPRK1PDE4DLMNAPDE3AADCY2 | |
| SCHEMBL11658080 | 0.62 | ATM (0.44) | OPRK1PDE4DMEN1KMT2AGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4520196-A | α-Mercaptophenylacetic acid derivatives of imidazole-containing compounds and analogues thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |