Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320987 | 0.92 | MEN1 (0.38) | MAPTMEN1HTTKMT2AGSK3B | |
| SCHEMBL10809610 | 0.65 | ITGB2 (0.51) | LMNAMAPTHTR7MEN1KMT2A | |
| SCHEMBL11014231 | 0.64 | OPRK1 (0.37) | LMNAMEN1HTTKMT2A | |
| SCHEMBL11272811 | 0.64 | SRD5A1 (0.37) | LMNAMAPTMEN1HTTKMT2A | |
| SCHEMBL10509753 | 0.62 | ALOX15 (0.50) | LMNAMAPTMEN1HTTKMT2A | |
| SCHEMBL10808729 | 0.61 | GSK3B (0.41) | LMNAMAPTMEN1KMT2ASRD5A1 | |
| SCHEMBL10672173 | 0.59 | OPRK1 (0.37) | LMNA | |
| SCHEMBL7269675 | 0.59 | CA2 (0.40) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27034742 | 0.58 | GRIA1 (0.38) | LMNAMAPTHTR7MEN1KMT2A | |
| SCHEMBL10507148 | 0.57 | ALOX15 (0.53) | LMNAMAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021773-B1 | THIAZOLO (2,3-B) BENZO (AND AZABENZO) THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-01 | — | — | EP | claimed |
| US-4275065-A | USEFUL FOR SKIN GRAFTS AND ORGAN TRANSPLANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-23 | — | — | US | claimed |
| EP-0021773-B1 | THIAZOLO (2,3-B) BENZO (AND AZABENZO) THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-01 | — | — | EP | disclosed |
| US-4275065-A | USEFUL FOR SKIN GRAFTS AND ORGAN TRANSPLANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-23 | — | — | US | disclosed |
| EP-0021773-A1 | Thiazolo (2,3-b) benzo (and azabenzo) thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-01-07 | — | — | EP | disclosed |