Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211367 | 0.87 | MAPT (0.56) | LIG1MAPTHPGDLMNAHTT | |
| SCHEMBL3467787 | 0.85 | MAPT (0.49) | MAPTHPGDLMNAHTTALDH1A1 | |
| SCHEMBL3879139 | 0.85 | GAA (0.55) | LIG1MAPTHPGDLMNAHTT | |
| SCHEMBL4132989 | 0.83 | NPC1 (0.42) | MAPTHPGDHTTALDH1A1MAPK1 | |
| SCHEMBL11947075 | 0.77 | ALDH1A1 (0.68) | MAPTHPGDLMNAHTTPKM | |
| SCHEMBL1758224 | 0.76 | HTT (0.60) | LIG1MAPTHPGDLMNAHTT | |
| SCHEMBL30355061 | 0.76 | HTT (0.60) | LIG1MAPTHPGDLMNAHTT | |
| SCHEMBL93340 | 0.76 | HDAC1 (0.66) | LIG1MAPTHPGDLMNAHTT | |
| SCHEMBL29366288 | 0.76 | HDAC1 (0.66) | LIG1MAPTHPGDLMNAHTT | |
| Hydroquinone SCHEMBL10426480 | 0.76 | ACHE (0.56) | MAPTHPGDLMNAHTTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141319-A2 | Substituted phenoxyalcanoic-acid ester | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-05-15 | — | — | EP | disclosed |
| EP-0140050-A1 | Heat sensitive record material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-05-08 | — | — | EP | disclosed |
| EP-0068260-A2 | Substituted phenoxypropionates, process for their preparation and their use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-01-05 | — | — | EP | disclosed |