Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 17/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018192 | 0.93 | MAPT (0.48) | CHEK2MAPTL3MBTL1PDE4APDE4B | |
| SCHEMBL11019284 | 0.88 | CHEK2 (0.55) | CHEK2 | |
| SCHEMBL11020406 | 0.85 | CHEK2 (0.56) | CHEK2 | |
| SCHEMBL11019646 | 0.84 | MAPT (0.47) | CHEK2MAPTL3MBTL1PDE4APDE4B | |
| SCHEMBL11021561 | 0.83 | L3MBTL1 (0.47) | CHEK2MAPTL3MBTL1PDE4APDE4B | |
| SCHEMBL11019277 | 0.80 | CHEK2 (0.46) | CHEK2MAPT | |
| SCHEMBL11017899 | 0.79 | CHEK2 (0.50) | CHEK2MAPTL3MBTL1PDE4APDE4B | |
| SCHEMBL11018668 | 0.78 | KDM4E (0.48) | CHEK2MAPTL3MBTL1 | |
| SCHEMBL11016890 | 0.77 | CHEK2 (0.63) | CHEK2 | |
| SCHEMBL11021552 | 0.77 | L3MBTL1 (0.47) | MAPTL3MBTL1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |