Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019583 | 0.85 | SMN1; SMN2 (0.57) | SIRT2CTSVCTSLARALDH1A1 | |
| SCHEMBL11020058 | 0.84 | SIRT2 (0.61) | SIRT2CTSVCTSLARALDH1A1 | |
| SCHEMBL10834337 | 0.81 | CTSV (0.69) | SIRT2CTSVCTSLARSMN1; SMN2 | |
| SCHEMBL10934422 | 0.80 | SIRT2 (0.60) | SIRT2CTSVCTSLARALDH1A1 | |
| SCHEMBL11020507 | 0.78 | MAPT (0.49) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL2954443 | 0.74 | MAPT (0.60) | MAPT | |
| SCHEMBL560896 | 0.74 | MRGPRX4 (0.54) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL11714868 | 0.73 | MEN1 (0.67) | SIRT2ARALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL197223 | 0.72 | LMNA (0.67) | ARSMN1; SMN2MAOBMAPTCYP1A2 | |
| SCHEMBL695575 | 0.71 | ALOX5 (0.53) | SMN1; SMN2MAOBMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496590-A | TREATMENT OR PREVENTION OF ALLERGIC ASTHMA, ANTI-ASTHMATIC | STERLING DRUG INC. (US) | 1985-01-29 | — | — | US | claimed |
| US-4496590-A | TREATMENT OR PREVENTION OF ALLERGIC ASTHMA, ANTI-ASTHMATIC | STERLING DRUG INC. (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0122518-A1 | Phenylaminobenzenealkanols and preparation | STERLING DRUG INC. (US) | 1984-10-24 | — | — | EP | disclosed |