Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015988 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL11021116 | 0.90 | HTT (0.48) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL3528024 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL3532279 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL3294463 | 0.83 | MEN1 (0.45) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL9955978 | 0.83 | MEN1 (0.51) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL538288 | 0.81 | THRB (0.43) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL16446231 | 0.80 | RAB9A (0.46) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL11020554 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TDP1POLBMAPTHPGD | |
| SCHEMBL3723384 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TDP1POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153580-A1 | Naphthyridine antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-09-04 | — | — | EP | disclosed |