Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818793 | 0.82 | ADORA3 (0.51) | CNR2ADORA3ADORA2AADORA1 | |
| SCHEMBL14959118 | 0.77 | MGAM (0.59) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL6810627 | 0.76 | POLB (0.43) | PARP1ALDH1A1POLB | |
| SCHEMBL1917210 | 0.75 | MGAM (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL10397230 | 0.74 | PDE10A (0.57) | MGAMGAASIMGAM2DDAH1 | |
| SCHEMBL7964155 | 0.74 | CHEK1 (0.58) | GAAPARP1L3MBTL1DDAH1POLB | |
| SCHEMBL9754832 | 0.74 | ALDH1A1 (0.46) | ALDH1A1ADORA3ADORA2AADORA1DDAH1 | |
| SCHEMBL1917492 | 0.74 | PSMB8 (0.49) | MGAMGAASIMGAM2HPGD | |
| SCHEMBL4366276 | 0.74 | KMT2A (0.44) | HPGDPARP1ALDH1A1DDAH1POLB | |
| SCHEMBL14958589 | 0.74 | GAA (0.51) | MGAMGAASIMGAM2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138750-A1 | Process for the production of substituted benzimidazoles | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |