Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871299 | 0.88 | POLB (0.44) | POLBPARP1ALDH1A1 | |
| SCHEMBL29968130 | 0.88 | POLB (0.44) | POLBPARP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8814858 | 0.80 | POLB (0.45) | POLBPARP1PDE5APDE4APDE4B | |
| SCHEMBL9754832 | 0.79 | ALDH1A1 (0.46) | POLBALDH1A1 | |
| SCHEMBL6755252 | 0.78 | MGAM (0.45) | POLBALDH1A1 | |
| SCHEMBL3245583 | 0.77 | PDE10A (0.54) | POLBPARP1ALDH1A1 | |
| SCHEMBL11020599 | 0.76 | MGAM (0.49) | POLBPARP1ALDH1A1 | |
| SCHEMBL6917378 | 0.76 | PARP1 (0.43) | POLBPARP1 | |
| SCHEMBL8818793 | 0.75 | ADORA3 (0.51) | — | |
| SCHEMBL3857628 | 0.74 | POLB (0.47) | POLBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113351-A2 | BIFUNCTIONAL AMINO-BORON LEWIS ACID - LEWIS BASE CATALYST | UNIVERSITY OF DURHAM (GB) | 2004-12-29 | — | — | WO | disclosed |