Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020867 | 0.93 | TP53 (0.51) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL11019173 | 0.90 | POLB (0.47) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL11019650 | 0.84 | CHEK2 (0.43) | SMN1; SMN2LMNAHPGDTP53RHEB | |
| SCHEMBL11019181 | 0.83 | TP53 (0.55) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL11016885 | 0.83 | CHEK2 (0.53) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL11017086 | 0.79 | DHFR (0.42) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL10760161 | 0.79 | RHEB (0.47) | SMN1; SMN2LMNAHPGDRHEBNPC1 | |
| SCHEMBL11019019 | 0.79 | HPSE (0.42) | SMN1; SMN2HPGDMEN1KMT2ATP53 | |
| SCHEMBL11018034 | 0.79 | RHEB (0.39) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL11019640 | 0.78 | MAPT (0.47) | SMN1; SMN2LMNAMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |