Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517401 | 0.77 | LMNA (0.33) | CYP1A2LMNA | |
| SCHEMBL25425473 | 0.74 | AKR1B1 (0.34) | TSHRPPARD | |
| SCHEMBL872318 | 0.72 | ALDH1A1 (0.33) | CYP1A2TSHRLMNA | |
| SCHEMBL10811536 | 0.69 | ALDH1A1 (0.36) | — | |
| SCHEMBL9637983 | 0.69 | CYP2D6 (0.42) | TSHRLMNA | |
| SCHEMBL27431643 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL2950319 | 0.67 | — | — | |
| SCHEMBL30541809 | 0.67 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL4835941 | 0.67 | FDPS (0.33) | PPARD | |
| SCHEMBL11021142 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030424-B1 | DERIVATIVES OF 4-(METHYLPHOSPHINYL)-2-OXOBUTANOIC ACID, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND INTERMEDIATES AND METHODS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-20 | — | — | EP | claimed |
| EP-0030424-A2 | Derivatives of 4-(methylphosphinyl)-2-oxobutanoic acid, herbicidal compositions containing them, and intermediates and methods for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | claimed |
| EP-0030424-B1 | DERIVATIVES OF 4-(METHYLPHOSPHINYL)-2-OXOBUTANOIC ACID, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND INTERMEDIATES AND METHODS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-20 | — | — | EP | disclosed |
| US-4399287-A | POSTEMERGENCE HERBICIDES; PESTICIDES; PLANT GROWTH REGULATORS; DESICCANTS | FBC LIMITED (GB) | 1983-08-16 | — | — | US | disclosed |
| EP-0030424-A2 | Derivatives of 4-(methylphosphinyl)-2-oxobutanoic acid, herbicidal compositions containing them, and intermediates and methods for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |