Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339057 | 0.89 | HPGD (0.44) | LIG1LMNAHSD17B10ALDH1A1KMT2A | |
| SCHEMBL5144207 | 0.88 | LMNA (0.44) | LMNAHSD17B10ALDH1A1KMT2AMAPT | |
| Iodide SCHEMBL11214733 | 0.86 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MAPTKDM4E | |
| SCHEMBL11023732 | 0.85 | NPC1 (0.40) | LIG1LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL2221653 | 0.80 | MDM2 (0.48) | LMNAALDH1A1KMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL2356480 | 0.78 | MDM2 (0.47) | LMNAALDH1A1KMT2AMAPTKDM4E | |
| Water SCHEMBL16320768 | 0.78 | MDM2 (0.47) | LMNAALDH1A1KMT2AMAPTKDM4E | |
| Iodide SCHEMBL2353850 | 0.78 | MDM2 (0.47) | LMNAALDH1A1KMT2AMAPTKDM4E | |
| Bromide SCHEMBL2356766 | 0.78 | MDM2 (0.47) | LMNAALDH1A1KMT2AMAPTKDM4E | |
| Iodide SCHEMBL9636643 | 0.78 | TERT (0.41) | LMNAHSD17B10ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060059-B1 | METHOD FOR DETERMINING THE ACTIVITY OF CHOLINESTERASE AND DIAGNOSTIC SOLUTION FOR USE THEREIN | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1985-08-21 | — | — | EP | claimed |