Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020500 | 0.90 | CA12 (0.46) | POLBCA12CA1CA2CA6 | |
| SCHEMBL10339057 | 0.86 | HPGD (0.44) | NPC1CA12CA1CA2CA6 | |
| SCHEMBL11022263 | 0.85 | LIG1 (0.49) | NPC1RAB9APOLBCA12CA1 | |
| Iodide SCHEMBL9636643 | 0.77 | TERT (0.41) | POLBCA12CA1CA2CA9 | |
| SCHEMBL2221653 | 0.76 | MDM2 (0.48) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL9635153 | 0.75 | CA5A (0.42) | CA12CA1CA2CA9LMNA | |
| Water SCHEMBL16320768 | 0.75 | MDM2 (0.47) | NPC1RAB9ACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL2356480 | 0.75 | MDM2 (0.47) | NPC1RAB9ACA12CA1CA2 | |
| Iodide SCHEMBL2353850 | 0.75 | MDM2 (0.47) | NPC1RAB9ACA12CA1CA2 | |
| Bromide SCHEMBL2356766 | 0.75 | MDM2 (0.47) | NPC1RAB9ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060059-B1 | METHOD FOR DETERMINING THE ACTIVITY OF CHOLINESTERASE AND DIAGNOSTIC SOLUTION FOR USE THEREIN | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1985-08-21 | — | — | EP | claimed |