Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10492644 | 0.81 | ALDH1A1 (0.39) | KIF11KCNN4ALDH1A1MAPK1MAPT | |
| SCHEMBL308613 | 0.78 | ALDH1A1 (0.39) | KCNN4ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL24029860 | 0.77 | KCNN4 (0.48) | KIF11KCNN4ALDH1A1MAPK1TSHR | |
| SCHEMBL2570700 | 0.77 | KIF11 (0.47) | KIF11ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL31481037 | 0.75 | KIF11 (0.50) | KIF11ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL8543828 | 0.73 | SMN1; SMN2 (0.46) | KIF11ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL18156891 | 0.73 | KIF11 (0.44) | KIF11KCNN4ALDH1A1MAPK1LMNA | |
| SCHEMBL10838619 | 0.72 | CYP3A4 (0.41) | ALDH1A1MAPK1LMNAMAPTTDP1 | |
| SCHEMBL4580674 | 0.72 | ESR1 (0.60) | KCNN4ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL24030026 | 0.71 | ESR1 (0.48) | ALDH1A1MAPK1TSHRESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069065-B1 | PROCESS FOR THE ALKYLATION OR ARALKYLATION OF AROMATIC AMINES | CIBA-GEIGY AG (CH) | 1985-02-13 | — | — | EP | disclosed |
| US-4436936-A | ACID CATALYSTS | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0069065-A1 | Process for the alkylation or aralkylation of aromatic amines | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | disclosed |