Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624956 | 0.88 | MAPT (0.39) | ALDH1A1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL10492644 | 0.85 | ALDH1A1 (0.39) | ALDH1A1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL11020376 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL10492504 | 0.82 | ESR1 (0.43) | ALDH1A1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL3751989 | 0.79 | CYP3A4 (0.45) | ALDH1A1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL11022580 | 0.78 | KIF11 (0.43) | ALDH1A1CYP3A4ESR1ESR2TAAR1 | |
| Hydrochloric Acid SCHEMBL3291595 | 0.78 | CYP3A4 (0.43) | ALDH1A1CYP3A4ESR1ESR2TAAR1 | |
| Bromide SCHEMBL7776359 | 0.78 | CYP3A4 (0.43) | ALDH1A1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL10492679 | 0.76 | CYP3A4 (0.38) | ALDH1A1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL29697590 | 0.75 | ESR1 (0.49) | ALDH1A1CYP3A4ESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503774-B1 | Optical recording medium | CANON KK (JP) | 1997-05-14 | — | — | EP | claimed |
| US-9795549-B2 | 1,2-alkane polyol-containing composition | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20160045414-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
| EP-2985017-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | Osaka Organic Chemical Ind., Ltd. (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-8642690-B2 | Bis [tri (hydroxypolyalkyleneoxy) silylalkyl] polysulfide, method of manufacturing bis [tri (hydroxypolyalkyleneoxy) silylalkyl] polysulfide, tire rubber additive, and tire rubber composition | DOW CORNING CORPORATION (US) | 2014-02-04 | — | — | US | disclosed |
| US-8093323-B2 | Method for manufacturing a bis(silatranylalkyl) polysulfide, method for manufacturing a mixture of bis(silatranylalkyl) polysulfide etc., a mixture of bis(silatranylalkyl) polysulfide etc., and rubber composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-20110040000-A1 | Bis [Tri (Hydroxypolyalkyleneoxy) Silylalkyl] Polysulfide, Method of Manufacturing Bis [Tri (Hydroxypolyalkyleneoxy) Silylalkyl] Polysulfide, Tire Rubber Additive, And Tire Rubber Composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-02-17 | — | — | US | disclosed |
| EP-2125836-B1 | BISÝTRI(HYDROXYPOLYALKYLENEOXY)SILYLALKYL¨POLYSULFIDE, METHOD OF MANUFACTURING BISÝTRI(HYDROXYPOLYALKYLENEOXY)SILYLALKYL¨POLYSULFIDE, TIRE RUBBER ADDITIVE, AND TIRE RUBBER COMPOSITION | DOW CORNING TORAY CO LTD (JP) | 2010-09-22 | — | — | EP | disclosed |
| US-20100120950-A1 | Method for Manufacturing A Bis(Silatranylalkyl) Polysulfide, Method for Manufacturing a Mixture of Bis(Silatranylalkyl) Polysulfide etc., A Mixture of Bis(Silatranylalkyl) Polysulfide etc., and Rubber Composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-05-13 | — | — | US | disclosed |
| CN-101451005-A | Antishock insulation rubber member for high-tension cable | JICHAO WANG (CN) | 2009-06-10 | — | — | CN | disclosed |
| US-5046542-A | Radial tires for construction vehicles including tread cap and divided tread base | BRIDGESTONE CORPORATION (JP) | 1991-09-10 | — | — | US | disclosed |
| US-5043388-A | Mixing vulcanizable rubber, fiber forming polyamide, and alkylphenol-formaldehyde resole; controlled temperature extrusion | UBE INDUSTRIES, INC. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-5034465-A | Butadiene-styrene copolymers and hydrogenated copolymers for tires | BRIDGESTONE CORPORATION (JP) | 1991-07-23 | — | — | US | disclosed |
| US-4598110-A | MOLDING MATERIALS | KANEBO LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| US-4596845-A | Spherical particles of diameters of 0.1 to 150 microns, filler | KANEBO LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4558089-A | STORAGE-STABLE AND FREE-FLOWING RUBBERY THERMOPLASTIC MOLDING MATERIALS | KANEBO LTD. (JP) | 1985-12-10 | — | — | US | disclosed |
| US-4476277-A | IN A THERMOPLASTIC RESIN-MOLDING MATERIAL | KANEBO LTD. (JP) | 1984-10-09 | — | — | US | disclosed |
| US-4300970-A | Method of bonding vulcanized rubber to resin | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4257468-A | P-PHENYLENDIAMINE TYPE ANTIOXIDANT | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1981-03-24 | — | — | US | disclosed |
| US-3979358-A | MERCAPTOBENZO-1,3-DIAZOLE, PHENYLENEDIAMINE COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JA) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120950-A1 | Method for Manufacturing A Bis(Silatranylalkyl) Polysulfide, Method for Manufacturing a Mixture of Bis(Silatranylalkyl) Polysulfide etc., A Mixture of Bis(Silatranylalkyl) Polysulfide etc., and Rubber Composition | TST, SGMS2, SSR3 | ALDH1A1 2868/4885CYP3A4 2101/4885ESR1 4428/4885 |
| US-20110040000-A1 | Bis [Tri (Hydroxypolyalkyleneoxy) Silylalkyl] Polysulfide, Method of Manufacturing Bis [Tri (Hydroxypolyalkyleneoxy) Silylalkyl] Polysulfide, Tire Rubber Additive, And Tire Rubber Composition | TMSB10, SSR1, HPSE | ALDH1A1 3498/4885CYP3A4 2297/4885ESR1 2802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.