Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9635124 | 0.98 | CA5A (0.41) | CA5ACA12CA1CA2CA7 | |
| SCHEMBL11020500 | 0.83 | CA12 (0.46) | CA12CA1CA2CA9FASN | |
| SCHEMBL5144207 | 0.81 | LMNA (0.44) | CA5ACA12CA1CA2CA7 | |
| Iodide SCHEMBL11214733 | 0.80 | LMNA (0.42) | CA5ACA12CA1CA2CA7 | |
| SCHEMBL11021523 | 0.77 | KDM4E (0.56) | CA12CA1CA2CA7CA9 | |
| Iodide SCHEMBL9636197 | 0.76 | KDM4E (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2221653 | 0.76 | MDM2 (0.48) | CA5ACA12CA1CA2CA7 | |
| Iodide SCHEMBL10522536 | 0.75 | CES2 (0.49) | MAPTTSHRADRB2 | |
| Hydrochloric Acid SCHEMBL2356480 | 0.74 | MDM2 (0.47) | CA5ACA12CA1CA2CA7 | |
| Iodide SCHEMBL2353850 | 0.74 | MDM2 (0.47) | CA5ACA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241915-B1 | METHOD FOR DETERMINING CHOLINESTERASE ACTIVITY | NITTO BOSEKI CO., LTD. (JP) | 1992-07-08 | — | — | EP | claimed |