Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083791 | 0.86 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL29049638 | 0.77 | GABRA1 (0.45) | CYP3A4GABRA1GABRB2POLBMEN1 | |
| SCHEMBL2420372 | 0.77 | PKM (0.47) | GABRA1GABRB2TDP1KMT2AALDH1A1 | |
| SCHEMBL2875381 | 0.74 | AKR1B1 (0.52) | CYP1A2CYP2C19GABRA1GABRB2HPGD | |
| SCHEMBL29944951 | 0.74 | AKR1B1 (0.57) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL2550830 | 0.74 | AKR1B1 (0.57) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL2403346 | 0.73 | GABRA1 (0.76) | CYP1A2CYP2D6CYP2C19GABRA1GABRB2 | |
| SCHEMBL31607049 | 0.73 | HSD17B10 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL10483799 | 0.73 | POLB (0.64) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL11028284 | 0.73 | GABRA1 (0.40) | GABRA1GABRB2TDP1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044119-B1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | STAMICARBON B.V. (NL) | 1985-05-29 | — | — | EP | disclosed |
| US-4435552-A | COORDINATION CATALYST CONTAINING HALOACYL COMPOUND | STAMICARBON B.V. (NL) | 1984-03-06 | — | — | US | disclosed |
| EP-0044119-A2 | Process for the preparation of copolymers of ethylene with at least one other 1-alkene | STAMICARBON B.V. (NL) | 1982-01-20 | — | — | EP | disclosed |