Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | FER | P16591 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11890574 | 1.00 | FLT3 (0.54) | FLT3LRRK2KMT2AMEN1AGTR1 | |
| SCHEMBL31491093 | 0.90 | LRRK2 (0.50) | FLT3LRRK2KMT2AMEN1AGTR1 | |
| SCHEMBL16583648 | 0.86 | FLT3 (0.48) | FLT3LRRK2KMT2AMEN1AGTR1 | |
| SCHEMBL21480103 | 0.86 | MAOA (0.50) | FLT3LRRK2KMT2AMEN1AGTR1 | |
| SCHEMBL3848509 | 0.86 | MAOA (0.50) | FLT3LRRK2KMT2AMEN1AGTR1 | |
| SCHEMBL2589272 | 0.83 | LRRK2 (0.57) | LRRK2KMT2AMEN1KDRACVR1 | |
| SCHEMBL2589274 | 0.83 | LRRK2 (0.57) | LRRK2KMT2AMEN1KDRACVR1 | |
| Isoindigo SCHEMBL9899736 | 0.83 | LRRK2 (0.67) | LRRK2KDRACVR1MAOAMAOB | |
| Isoindigo SCHEMBL9899740 | 0.83 | LRRK2 (0.67) | LRRK2KDRACVR1MAOAMAOB | |
| Isoindigo SCHEMBL12386233 | 0.83 | LRRK2 (0.67) | LRRK2KDRACVR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120190009-A1 | Viral Modulators and Processes Thereof | KASHANCHI FATAH (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190723-A1 | VIRAL MODULATORS AND PROCESSES THEREOF | KASHANCHI FATAH (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190723-A1 | VIRAL MODULATORS AND PROCESSES THEREOF | MAVS, HAVCR2, HDLBP | FLT3 3367/4885LRRK2 3338/4885KMT2A 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.