Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10805267 | 0.99 | SIGMAR1 (0.45) | SIGMAR1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL27033272 | 0.73 | KMT2A (0.49) | SIGMAR1HTR2AHTR2CHTR2BSLC6A9 | |
| SCHEMBL22069780 | 0.72 | SLC6A3 (0.41) | SIGMAR1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL27727732 | 0.69 | SLC6A3 (0.53) | SIGMAR1SLC6A3 | |
| Hydrochloric Acid SCHEMBL8093116 | 0.69 | OPRM1 (0.47) | SIGMAR1SLC6A3OPRM1SLC6A9LMNA | |
| SCHEMBL18838310 | 0.67 | SIGMAR1 (0.67) | SIGMAR1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL10806098 | 0.67 | SIGMAR1 (0.45) | SIGMAR1HTR2AHTR2CSLC6A3OPRM1 | |
| SCHEMBL5872163 | 0.66 | L3MBTL1 (0.71) | SIGMAR1SLC6A3SMN1; SMN2MAPTGAA | |
| SCHEMBL2132367 | 0.65 | L3MBTL1 (0.60) | SLC6A3TSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL11922748 | 0.64 | SIGMAR1 (1.00) | SIGMAR1SLC6A3DRD2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984003090-A1 | SUBSTITUTED 1-AZASPIRO AD4.5 BDDECANES AND 1-AZASPIRO AD5.5 BDUNDECANES | STRUPCZEWSKI JOSEPH T (US) | 1984-08-16 | — | — | WO | claimed |