Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975369 | 0.79 | PPARA (0.61) | PPARAPPARGLMNATSHRSMN1; SMN2 | |
| SCHEMBL24177730 | 0.78 | PPARA (0.68) | PPARAPPARGLMNATSHRSMN1; SMN2 | |
| SCHEMBL10979186 | 0.78 | PPARA (0.64) | PPARAPPARGLMNATSHRSMN1; SMN2 | |
| SCHEMBL10973734 | 0.78 | L3MBTL1 (0.55) | PPARAPPARGLMNATSHRSMN1; SMN2 | |
| SCHEMBL22221608 | 0.78 | TLR7 (0.60) | PPARAPPARGLMNATSHRSMN1; SMN2 | |
| SCHEMBL12573937 | 0.77 | PPARA (0.66) | PPARAPPARGLMNATSHRSMN1; SMN2 | |
| Etofibrate SCHEMBL3122 | 0.76 | L3MBTL1 (0.55) | PPARALMNATSHRSMN1; SMN2ABCB11 | |
| Etofibrate SCHEMBL8168409 | 0.76 | L3MBTL1 (0.55) | PPARALMNATSHRSMN1; SMN2ABCB11 | |
| Etofibrate SCHEMBL29801484 | 0.76 | L3MBTL1 (0.55) | PPARALMNATSHRSMN1; SMN2ABCB11 | |
| SCHEMBL12573936 | 0.76 | PPARA (0.86) | PPARAPPARGLMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515809-A | ANTICHOLESTEROL | ALFA FARMACEUTICI S.P.A. (IT) | 1985-05-07 | — | — | US | disclosed |
| US-4378373-A | Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity | ALFA FARMACEUTICI S.P.A. (IT) | 1983-03-29 | — | — | US | disclosed |
| US-4296125-A | Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity | ALPHA FARMACEUTICI S.P.A. (IT) | 1981-10-20 | — | — | US | disclosed |