Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519738 | 0.89 | LMNA (0.49) | LMNAPOLBHPGDHSD11B1 | |
| SCHEMBL11031281 | 0.86 | TBXAS1 (0.52) | SLC6A2SLC6A4SLC6A3EPHX2LMNA | |
| SCHEMBL17968651 | 0.81 | ALDH1A1 (0.38) | LMNAHTTSMN1; SMN2GAA | |
| SCHEMBL170301 | 0.80 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3EPHX2LMNA | |
| SCHEMBL11029028 | 0.80 | ALDH1A1 (0.52) | SLC6A2SLC6A4SLC6A3LMNAKCNA5 | |
| Hydrochloric Acid SCHEMBL128794 | 0.79 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3EPHX2LMNA | |
| SCHEMBL2203786 | 0.77 | CYP2C19 (0.56) | SLC6A2SLC6A4SLC6A3EPHX2LMNA | |
| SCHEMBL8672694 | 0.77 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3EPHX2LMNA | |
| SCHEMBL10919976 | 0.77 | CYP19A1 (0.50) | LMNAHTTSMN1; SMN2HPGD | |
| SCHEMBL20747091 | 0.75 | RIPK1 (0.52) | LMNASMN1; SMN2HPGDHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477453-A | ANTISPASMODIC, ANTIHISTAMINE | UNIVABLOT (FR) | 1984-10-16 | — | — | US | disclosed |