Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 2-Allylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Allylphenol SCHEMBL11031219 | 1.00 | GABRA1 (0.38) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL9603869 | 0.92 | GABRA1 (0.43) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL7187336 | 0.83 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL5489315 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL1011363 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL9297407 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL5488913 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL4348728 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL18259392 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBALDH1A1 | |
| 2-Allylphenol SCHEMBL8863113 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508863-A | WITH BRANCHED ALPHA-OLEFINS OLIGOMERS | ARGUS CHEMICAL CORPORATION (US) | 1985-04-02 | — | — | US | claimed |