SCHEMBL1103323

SCHEMBL1103323

c1ccc2c(c1)CCc1ccccc1N2c1c2ccccc2c(N2c3ccccc3CCc3ccccc32)c2c1cnc1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MPO P05164 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GPR3 P46089 1/20 0.35
POLB P06746 1/20 0.32
ALOX15 P16050 1/20 0.32
NR4A1 P22736 1/20 0.32
PDPK1 O15530 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GRM5 P41594 2/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1103321 0.91 MPO (0.35) MPOLMNAKDM4EGPR3PDPK1
SCHEMBL1103442 0.87 TLR7 (0.35) MPOSMN1; SMN2LMNAKDM4EPOLB
SCHEMBL1103608 0.83 POLB (0.35) SMN1; SMN2LMNAKDM4EGPR3POLB
SCHEMBL1103328 0.82 ADORA3 (0.38) SMN1; SMN2LMNAKDM4EGPR3HTT
SCHEMBL1103312 0.82 KDM4E (0.35) MPOLMNAKDM4EGPR3PDPK1
SCHEMBL1103313 0.81 CDK4 (0.36) MPOSMN1; SMN2KDM4EGPR3PDPK1
SCHEMBL1103317 0.81 MAOA (0.35) SMN1; SMN2KDM4EGPR3PDPK1NPSR1
SCHEMBL1103555 0.81 MET (0.39) SMN1; SMN2LMNAKDM4EGPR3PDPK1
SCHEMBL1103326 0.79 TLR7 (0.35) KDM4EGPR3PDPK1GRM5
SCHEMBL1103316 0.79 PDPK1 (0.35) MPOSMN1; SMN2LMNAKDM4EGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
EP-2147962-A1 Azaanthracene-derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 MPO 965/4885SMN1; SMN2 4091/4885LMNA 2738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.