SCHEMBL1702787

SCHEMBL1702787

C=CCc1ccccc1Nc1ccc(-c2ccc(Nc3ccccc3CC=C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
MAPT P10636 6/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
MAPK1 P28482 1/20 0.38
JAK1 P23458 1/20 0.37
TYK2 P29597 1/20 0.37
JAK3 P52333 1/20 0.37
AKR1B1 P15121 1/20 0.36
KDM4E B2RXH2 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
APP P05067 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
SNCA P37840 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11034063 0.94 ADRA2B (0.44) ADRA2BADRA2CMAPTMEN1KMT2A
SCHEMBL6046931 0.89 MAPT (0.45) ADRA2BADRA2CMAPTMEN1KMT2A
SCHEMBL30729429 0.89 MAPT (0.45) ADRA2BADRA2CMAPTMEN1KMT2A
SCHEMBL7757717 0.88 ADRA2B (0.40) ADRA2BADRA2CMAPTMEN1KMT2A
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL11874052 0.86 ALDH1A1 (0.46) ADRA2BADRA2CMAPTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL20481810 0.85 MAPT (0.51) ADRA2BADRA2CMAPTMEN1KMT2A
SCHEMBL176287 0.85 ADRA2C (0.47) ADRA2BADRA2CMAPTMEN1KMT2A
SCHEMBL1727994 0.81 AKR1B1 (0.33) ADRA2BADRA2CMAPTMEN1KMT2A
SCHEMBL1173024 0.80 ALDH1A1 (0.47) ADRA2BADRA2CMAPTMEN1KMT2A
SCHEMBL9423214 0.80 ADRA2B (0.36) ADRA2BADRA2CMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080299484-A1 contacting binder resin, pigment and liquid to form Newtonian millbase, centrifuging to remove large particles and obtain supernatant, concentrating by recentrifugation, removing supernatant XEROX CORPORATION 2008-12-04 US claimed
US-7314694-B2 Photoconductive imaging members XEROX CORPORATION (US) 2008-01-01 US claimed
EP-1580608-B1 Reversibly color changing undercoat layer for electrophotographic photoreceptors XEROX CORP (US) 2007-01-10 EP claimed
US-20060240345-A1 Photoreceptors XEROX CORPORATION 2006-10-26 US claimed
US-7125634-B2 Reversibly color changing undercoat layer for electrophotographic photoreceptors XEROX CORPORATION (US) 2006-10-24 US claimed
US-20060222978-A1 Photoconductive imaging members XEROX CORPORATION 2006-10-05 US claimed
EP-1580608-A1 Reversibly color changing undercoat layer for electrophotographic photoreceptors Xerox Corporation (US) 2005-09-28 EP claimed
US-20050202330-A1 Reversibly color changing undercoat layer for electrophotographic photoreceptors XEROX CORPORATION 2005-09-15 US claimed
US-6660441-B2 Terpolymer of pyromellitic acid-bis/3,4-dicarboxyphenyl/ ether-phenylenediamine-p-benzoquinone polyetherimide support material; eliminates curling without using anticurl backing layer XEROX CORPORATION 2003-12-09 US claimed
US-6096927-A Process for removal and recovery of an arylamine compound XEROX CORPORATION (US) 2000-08-01 US claimed
US-6063533-A CHARGE GENERATING LAYERS COMPRISING BENZIMIDAZOLE PERYLENE PIGMENTS DISPERSED IN POLY-4,4'-DIPHENYL-1,1'-CYCLOHEXANE CARBONATE WHEN THE CHARGE TRANSPORTING LAYER CONTAINS AN ALKYL- AND ALKYLOXY-SUBSTITUTED DIARYLAMINE; PHOTOSENSITIVITY XEROX CORPORATION (US) 2000-05-16 US claimed
US-5300393-A Imaging members and processes for the preparation thereof XEROX CORPORATION (US) 1994-04-05 US claimed
US-8790853-B2 Charge generating composition XEROX CORPORATION (US) 2014-07-29 US disclosed
EP-1715008-B1 Phthalocyanine co-crystals for use in photoreceptors XEROX CORP (US) 2012-10-03 EP disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-8016968-B2 Process for producing an imaging member belt having an angular seam XEROX CORPORATION (US) 2011-09-13 US disclosed
EP-0186303-A1 Electrophotographic imaging members XEROX CORPORATION (US) 1986-07-02 EP disclosed
US-4584253-A CHARGE LAYERS-AROMATIC AMINES OR HYDRAZONES, POLYMERIC BINDERS, CELLULOSIC HOLE TRAPPING XEROX CORPORATION (US) 1986-04-22 US disclosed
US-4563408-A ELECTROGRAPHY XEROX CORPORATION (US) 1986-01-07 US disclosed
US-4536457-A Migration imaging process XEROX CORPORATION (US) 1985-08-20 US disclosed