Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14706719 | 0.79 | LMNA (0.65) | LMNAHTTSMN1; SMN2KCNH2MEN1 | |
| SCHEMBL22827732 | 0.78 | CA2 (0.61) | LMNAHPGDKDM4EHSD17B10CA1 | |
| SCHEMBL10964252 | 0.78 | NOS2 (0.60) | LMNAHTTSMN1; SMN2KCNH2MEN1 | |
| SCHEMBL11153098 | 0.77 | CA2 (0.58) | LMNASMN1; SMN2HPGDKDM4ETP53 | |
| SCHEMBL11758416 | 0.77 | CA12 (0.61) | CA1CA2ALDH1A1CA9CA12 | |
| SCHEMBL28820121 | 0.76 | KDM4E (0.54) | LMNAHTTSMN1; SMN2KCNH2MEN1 | |
| SCHEMBL8492279 | 0.74 | ERCC5 (0.67) | HTTSMN1; SMN2MEN1MAPTHPGD | |
| SCHEMBL28790697 | 0.72 | PTGES2 (0.42) | LMNAHTTSMN1; SMN2MEN1MAPT | |
| SCHEMBL27639016 | 0.71 | RAPGEF4 (0.42) | SMN1; SMN2MEN1MAPTHPGDKMT2A | |
| SCHEMBL11034578 | 0.71 | HTT (0.50) | LMNAHTTSMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4495365-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL CO. (US) | 1985-01-22 | — | — | US | disclosed |