Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13519029 | 0.84 | AKT1 (0.67) | MAPK1ALDH1A1TDP1LMNAPLA2G10 | |
| Phenylglyoxal SCHEMBL57493 | 0.82 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1LMNAKMT2A | |
| Phenylglyoxal SCHEMBL5716642 | 0.82 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1LMNAKMT2A | |
| Phenylglyoxal SCHEMBL16745575 | 0.82 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1LMNAKMT2A | |
| Phenylglyoxal SCHEMBL11116049 | 0.82 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1LMNAKMT2A | |
| Phenylglyoxal SCHEMBL1697192 | 0.82 | TDP1 (0.72) | MAPK1ALDH1A1TDP1LMNAPLA2G10 | |
| SCHEMBL3306440 | 0.81 | LMNA (0.55) | MAPK1ALDH1A1TDP1LMNAPLA2G10 | |
| SCHEMBL3306434 | 0.81 | LMNA (0.55) | MAPK1ALDH1A1TDP1LMNAPLA2G10 | |
| SCHEMBL3306429 | 0.81 | LMNA (0.55) | MAPK1ALDH1A1TDP1LMNAPLA2G10 | |
| SCHEMBL1247035 | 0.80 | PLA2G10 (0.69) | ALDH1A1TDP1LMNAPLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |