Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | EPOR | P19235 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191668 | 0.98 | ATM (0.50) | ATMTLR4TLR2AKR1C3MAOB | |
| SCHEMBL10547225 | 0.88 | ALDH1A1 (0.51) | ATMTLR4TLR2MAOBALOX5 | |
| SCHEMBL10543902 | 0.88 | ADAMTS5 (0.46) | ATMTLR4TLR2AKR1C3MAOB | |
| SCHEMBL10545617 | 0.88 | RELA (0.51) | ATMMAOBLTA4HALDH1A1GAA | |
| SCHEMBL20472367 | 0.88 | ALDH1A1 (0.59) | ATMTLR4TLR2MAOBMAPT | |
| SCHEMBL10550570 | 0.88 | ALDH1A1 (0.47) | ATMTLR4TLR2MAOBALOX5 | |
| SCHEMBL8454760 | 0.88 | NPSR1 (0.46) | ATMTLR4TLR2AKR1C3MAOB | |
| SCHEMBL10975899 | 0.85 | LTA4H (0.50) | TLR4TLR2LMNAMEN1KMT2A | |
| SCHEMBL10547654 | 0.84 | LTA4H (0.53) | ATMLTA4HALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10547098 | 0.83 | KMO (0.51) | ATMMEN1KMT2AHSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59042342-A | — | — | None | — | — | JP | disclosed |
| JP-S5942342-A | CARBOXYLIC ACID ESTER, ITS PREPARATION, AND INSECTICIDAL AND MITICIDAL AGENT HAVING LOW TOXICITY TO FISH AND CONTAINING SAID ESTER AS ACTIVE COMPONENT | SUMITOMO CHEM CO LTD | 1984-03-08 | — | — | JP | disclosed |