Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5041945 | 0.85 | FDPS (0.47) | FDPSNAPRTKDM4EKMT2ATBXAS1 | |
| SCHEMBL10744809 | 0.84 | FDPS (0.46) | FDPSNAPRTKDM4EKMT2ATBXAS1 | |
| SCHEMBL10646874 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL15258874 | 0.82 | ALDH1A1 (0.47) | FDPSNAPRTKDM4EKMT2ATBXAS1 | |
| SCHEMBL11035308 | 0.81 | SMN1; SMN2 (0.36) | KDM4EKMT2APOLBCYP3A4ALDH1A1 | |
| SCHEMBL2568949 | 0.79 | KDM4E (0.54) | FDPSNAPRTKDM4ETBXAS1LMNA | |
| SCHEMBL9280186 | 0.76 | NAPRT (0.54) | NAPRTKDM4EKMT2ATBXAS1MEN1 | |
| SCHEMBL27041597 | 0.75 | KDM4E (0.53) | FDPSNAPRTKDM4ETBXAS1LMNA | |
| SCHEMBL27041606 | 0.75 | KDM4E (0.53) | FDPSNAPRTKDM4ETBXAS1LMNA | |
| SCHEMBL11221097 | 0.74 | TBXAS1 (0.49) | NAPRTKDM4ETBXAS1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070185-A1 | Preparation of lower alkyl 2-formyl-3-(6-methyl-3-pyridinyl)-propionates | SMITHKLINE BECKMAN CORPORATION (US) | 1983-01-19 | — | — | EP | disclosed |
| EP-0070185-A1 | Preparation of lower alkyl 2-formyl-3-(6-methyl-3-pyridinyl)-propionates | SMITHKLINE BECKMAN CORPORATION (US) | 1983-01-19 | — | — | EP | disclosed |