Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PNMT | P11086 | 9/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.44 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.44 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.44 |
| ▸ | CD44 | P16070 | 1/20 | 0.44 |
| ▸ | MSN | P26038 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30213424 | 1.00 | GAA (0.55) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL16116108 | 1.00 | GAA (0.55) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL16115726 | 0.90 | GAA (0.54) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL10293160 | 0.90 | GAA (0.54) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL29697818 | 0.90 | GAA (0.54) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL10854713 | 0.83 | TDP2 (0.45) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL11035541 | 0.83 | TDP2 (0.45) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL3417137 | 0.83 | MAPT (0.47) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL13224204 | 0.83 | MAPT (0.47) | GAAMAPTPNMTADRA2AADRA2B | |
| SCHEMBL16135451 | 0.80 | MAPT (0.46) | GAAMAPTPNMTADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113481181-B | Recombinant esterase mutant, gene, engineering bacterium and application of recombinant esterase mutant in splitting (R, S) -indoline-2-ethyl formate | 浙江工业大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-113481181-A | Recombinant esterase mutant, gene, engineering bacterium and application of recombinant esterase mutant in splitting (R, S) -indoline-2-ethyl formate | 浙江工业大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-110592045-B | Recombinant esterase, gene, engineering bacterium and application of recombinant esterase to resolution of (R, S) -indoline-2-ethyl formate | 浙江工业大学 | 2021-04-06 | — | — | CN | disclosed |
| CN-109762768-B | Bacillus B8W22 and application thereof | 浙江工业大学 | 2020-08-21 | — | — | CN | disclosed |
| CN-110592045-A | Recombinant esterase, gene, engineering bacterium and application of recombinant esterase to resolution of (R, S) -indoline-2-ethyl formate | 浙江工业大学 | 2019-12-20 | — | — | CN | disclosed |
| CN-109762768-A | Bacillus B8W22 and its application | 浙江工业大学 | 2019-05-17 | — | — | CN | disclosed |
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |
| CN-105283443-A | Heterocyclic derivatives and use thereof | C & C RES LAB | 2016-01-27 | — | — | CN | disclosed |
| CN-104788328-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2015-07-22 | — | — | CN | disclosed |
| CN-101891680-B | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-10-29 | — | — | CN | disclosed |
| CN-101006076-B | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2010-09-29 | — | — | CN | disclosed |
| CN-1522246-B | Triamide-substituted indoles, benzofurans and benzothiophenes | PFIZER | 2010-04-21 | — | — | CN | disclosed |
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | MSD K.K. (JP) | 2009-10-22 | — | — | US | disclosed |
| CN-101460489-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2009-06-17 | — | — | CN | disclosed |
| EP-1939194-A1 | BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
| CN-101006076-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2007-07-25 | — | — | CN | disclosed |
| CN-1880304-A | Triamide-substituted indoles, benzofuranes and benzothiophenes | PFIZER (US) | 2006-12-20 | — | — | CN | disclosed |
| CN-1522246-A | Triamide-substituted indoles, benzofurans and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (MTP) and/or apolipoprotein B (APO B) secretion | �Ʒ� | 2004-08-18 | — | — | CN | disclosed |
| CN-1439006-A | Novel compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECH INC (US) | 2003-08-27 | — | — | CN | disclosed |
| CN-1265591-A | Coumpound | ZENECA LTD (GB) | 2000-09-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | PYCR1, CHRM1, MTR | GAA 4536/4885MAPT 4595/4885PNMT 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.