Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.42 |
| ▸ | CTSB | P07858 | 5/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10555284 | 0.95 | CTSB (0.49) | RENCTSBCTSK | |
| SCHEMBL11006634 | 0.79 | REN (0.49) | RENCTSBCTSKCTSLCTSS | |
| SCHEMBL11011753 | 0.76 | REN (0.47) | RENCTSBCTSKCTSLCTSS | |
| SCHEMBL11010919 | 0.75 | CTSB (0.44) | RENCTSBCTSKCTSLCTSS | |
| SCHEMBL10908290 | 0.75 | CTSK (0.52) | RENCTSBCTSKCTSL | |
| SCHEMBL7030418 | 0.74 | CTSL (0.50) | CTSBCTSKCTSLCTSSMME | |
| SCHEMBL10909792 | 0.74 | CTSB (0.55) | RENCTSBCTSK | |
| SCHEMBL9551368 | 0.73 | CTSL (0.54) | CTSBCTSKCTSLCTSS | |
| SCHEMBL9551274 | 0.73 | CTSL (0.54) | CTSBCTSKCTSLCTSS | |
| SCHEMBL9666956 | 0.73 | CTSL (0.54) | CTSBCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |