Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943620 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| SCHEMBL2978516 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Bromide SCHEMBL2177195 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL2175073 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL2520909 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL2173176 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Bromide SCHEMBL2177190 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Sulfuric Acid SCHEMBL2171810 | 0.91 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Sulfuric Acid SCHEMBL2171814 | 0.91 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| SCHEMBL3161073 | 0.90 | CHRNB2 (0.69) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2026-01-22 | — | — | US | claimed |
| EP-4561994-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | Genecode (EE) | 2025-06-04 | — | — | EP | claimed |
| CN-120035580-A | Novel piperazinyl sulfonamides and their use as neuroprotective and/or neurorestorative agents | 基因密码公司 | 2025-05-23 | — | — | CN | claimed |
| CN-119948015-A | Novel sulfonamides and their use as neuroprotective and/or nerve repair agents | 基因密码公司 | 2025-05-06 | — | — | CN | claimed |
| WO-2024079351-A1 | NOVEL PIPERAZINE-BASED SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2024-04-18 | — | — | WO | claimed |
| WO-2024023284-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2024-02-01 | — | — | WO | claimed |
| US-8247578-B2 | Process for production of aralkyloxypyrrolidine derivative | KANEKA CORPORATION (JP) | 2012-08-21 | — | — | US | claimed |
| US-20110224444-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | KANEKA CORPORATION (JP) | 2011-09-15 | — | — | US | claimed |
| EP-1947083-B1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | KANEKA CORP (JP) | 2010-11-10 | — | — | EP | claimed |
| US-20080306283-A1 | Process For Production of Aralkyloxypyrrolidine Derivative | KANEKA CORPORATION (JP) | 2008-12-11 | — | — | US | claimed |
| EP-1947083-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | Kaneka Corporation (JP) | 2008-07-23 | — | — | EP | claimed |
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2026-01-22 | — | — | US | disclosed |
| US-20250340565-A1 | CD73 INHIBITOR COMPOUNDS | ADORX THERAPEUTICS LTD (GB) | 2025-11-06 | — | — | US | disclosed |
| EP-4635494-A2 | AMIDO HETEROAROMATIC COMPOUNDS | Astrazeneca AB (SE) | 2025-10-22 | — | — | EP | disclosed |
| EP-4514782-B1 | AMIDO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES | ASTRAZENECA AB (SE) | 2025-09-10 | — | — | EP | disclosed |
| WO-2007119463-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES AS TPK1 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007119463-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES AS TPK1 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007024113-A1 | PROCESS FOR THE PREPARATION OF CHIRAL 3-HYDROXY PYRROLIDINE COMPOUND AND DERIVATIVES THEREOF HAVING HIGH OPTICAL PURITY | RSTECH CORPORATION (KR) | 2007-03-01 | — | — | WO | disclosed |
| US-20040049049-A1 | Stereoselective synthesis of 1,2-disubstituted cycloalkyls | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. | 2004-03-11 | — | — | US | disclosed |
| WO-2003105756-A2 | STEREOSELECTIVE SYNTHESIS OF 1,2-DISUBSTITUTED CYCLOALKYLS | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | CNR1, CDR2, SMN1; SMN2 | SLC6A2 747/4885SLC6A4 1793/4885SLC6A3 322/4885 |
| US-20250340565-A1 | CD73 INHIBITOR COMPOUNDS | ENTPD5, ENTPD1, NT5E | SLC6A2 1034/4885SLC6A4 1160/4885SLC6A3 953/4885 |
| US-20080306283-A1 | Process For Production of Aralkyloxypyrrolidine Derivative | HPD, HAAO, ARL1 | SLC6A2 2188/4885SLC6A4 1613/4885SLC6A3 1495/4885 |
| US-20040049049-A1 | Stereoselective synthesis of 1,2-disubstituted cycloalkyls | CYP8B1, AGTR1, AGTR2 | SLC6A2 4010/4885SLC6A4 4235/4885SLC6A3 4090/4885 |
| US-20110224444-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | HPD, HAAO, ARL1 | SLC6A2 2188/4885SLC6A4 1613/4885SLC6A3 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.