Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2978516 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| SCHEMBL110365 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Bromide SCHEMBL2177195 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL2175073 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL2520909 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL2173176 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Bromide SCHEMBL2177190 | 0.98 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Sulfuric Acid SCHEMBL2171810 | 0.91 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| Sulfuric Acid SCHEMBL2171814 | 0.91 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 | |
| SCHEMBL3161073 | 0.90 | CHRNB2 (0.69) | SLC6A2SLC6A4SLC6A3KCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610122-A | Preparation method of trans-2-[(3R)-3-benzyloxy-1-pyrrolidinyl]-1-cyclohexanol | UNIV CHINA PHARMA | 2015-05-13 | — | — | CN | claimed |
| WO-2025245046-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| US-12018029-B2 | Hexahydropyrrolo[3,4-c]pyrrole derivatives useful as LOX inhibitors | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-06-25 | — | — | US | disclosed |
| US-12018029-B2 | Hexahydropyrrolo[3,4-c]pyrrole derivatives useful as LOX inhibitors | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-06-25 | — | — | US | disclosed |
| WO-2022140527-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| US-20210238179-A1 | HEXAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES USEFUL AS LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2021-08-05 | — | — | US | disclosed |
| US-20210238179-A1 | HEXAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES USEFUL AS LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2021-08-05 | — | — | US | disclosed |
| US-20210053972-A1 | COMPOUNDS USEFUL AS IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2021-02-25 | — | — | US | disclosed |
| CN-112243440-A | Hexahydroxypyrrolo [3,4-c ] pyrrole derivatives useful as LOX inhibitors | 癌症研究协会皇家癌症医院 | 2021-01-19 | — | — | CN | disclosed |
| EP-3743425-A1 | 2,8-DIACYL-2,8-DIAZASPIRO[5.5]UNDECANE COMPOUNDS USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2020-12-02 | — | — | EP | disclosed |
| US-20070254945-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2007-11-01 | — | — | US | disclosed |
| US-20070197632-A1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070099983-A1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP. (CA) | 2007-05-03 | — | — | US | disclosed |
| WO-2007024113-A1 | PROCESS FOR THE PREPARATION OF CHIRAL 3-HYDROXY PYRROLIDINE COMPOUND AND DERIVATIVES THEREOF HAVING HIGH OPTICAL PURITY | RSTECH CORPORATION (KR) | 2007-03-01 | — | — | WO | disclosed |
| US-20060247300-A1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP (CA) | 2006-11-02 | — | — | US | disclosed |
| EP-1666459-A2 | Aminocyclohexyl ether compounds and uses thereof | Cardiome Pharma Corp. (CA) | 2006-06-07 | — | — | EP | disclosed |
| EP-1560812-B1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP (CA) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005097087-A2 | MERGED ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2005-10-20 | — | — | WO | disclosed |
| US-20040049049-A1 | Stereoselective synthesis of 1,2-disubstituted cycloalkyls | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. | 2004-03-11 | — | — | US | disclosed |
| WO-2003105756-A2 | STEREOSELECTIVE SYNTHESIS OF 1,2-DISUBSTITUTED CYCLOALKYLS | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053972-A1 | COMPOUNDS USEFUL AS IMMUNOMODULATORS | CD74, HLA-DRB1, CD47 | SLC6A2 4227/4885SLC6A4 4457/4885SLC6A3 4462/4885 |
| US-12018029-B2 | Hexahydropyrrolo[3,4-c]pyrrole derivatives useful as LOX inhibitors | LOX, LOXL1, LOXL3 | SLC6A2 4512/4885SLC6A4 4183/4885SLC6A3 3529/4885 |
| US-20070254945-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885SLC6A4 1837/4885SLC6A3 2179/4885 |
| US-20070197632-A1 | Aminocyclohexyl ether compounds and uses thereof | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885SLC6A4 1837/4885SLC6A3 2179/4885 |
| US-20210238179-A1 | HEXAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES USEFUL AS LOX INHIBITORS | LOX, LOXL1, LOXL3 | SLC6A2 4512/4885SLC6A4 4183/4885SLC6A3 3529/4885 |
| US-20070099983-A1 | Aminocyclohexyl ether compounds and uses thereof | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885SLC6A4 1837/4885SLC6A3 2179/4885 |
| US-20040049049-A1 | Stereoselective synthesis of 1,2-disubstituted cycloalkyls | CYP8B1, AGTR1, AGTR2 | SLC6A2 4010/4885SLC6A4 4235/4885SLC6A3 4090/4885 |
| US-20060247300-A1 | Aminocyclohexyl ether compounds and uses thereof | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885SLC6A4 1837/4885SLC6A3 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.